摘要
目的:探讨高同型半胱氨酸血症(HHcy)与老年冠心病的相关性。方法:128例在我院行冠脉造影检查的老年患者,依据冠脉造影结果分为冠心病组(86例)和非冠心病组(42例)。比较两组患者血清同型半胱氨酸(Hcy)水平;以冠脉病变数目和血清Hcy值行Spearman相关性检验。结果:与非冠心病组比较,冠心病组血清Hcy水平明显增高(P〈0.01),冠脉病变数目与血清Hcy值之间相关系数r=0.667(P〈0.01)。表明冠脉病变数目和血清Hcy值成正相关。结论:血清Hcy水平和老年冠心病存在明显相关性,是老年冠心病的一个危险因素。
OBJECTIVE : To explore of the relationship between hyperhomocysteine (HHcy) and coronary heart disease (GHD) in the elderly. METHODS: Total 128 elderly patients in our hospital were divided into CHD group (86 cases) and non -CHD group (42 cases) according to the result of coronary angiography. The homocysteine (Hcy) levels were compared in two groups. Spearman correlation test was carried out between the number of lesions in coronary arteries and serum Hcy value. RESULTS : Serum Hcy levels were significantly higher in CHD group than those in non - CHD group (P 〈 0. 01 ). The correlation coefficient between the number of coronary lesions and serum Hcy values was 0. 497 (P 〈 0. 01 ), which indicated that there was a positive relation between them. CONCLUSION: There is a significant relation between the CHD and serum Hcy values. HHcy is a risk factor for coronary heart dis-ease in the elderly.
出处
《国际老年医学杂志》
2014年第6期241-243,共3页
International Journal of Geriatrics
关键词
冠心病
高同型半胱氨酸血症
冠脉造影
Coronary heart disease
Hyperhomocysteinemia
Coronary angiography