丁酸菌与老年肠道功能的相关性

The correlation of Butyric acid bacteria and elderly intestinal function

丁酸菌是一种专性厌氧芽胞杆菌,是以丁酸为主要代谢产物的益生菌,可定植于人体肠道,在某种程度上与乳酸菌有协同作用,可抑制人肠道内有害菌的生长、促进营养物质的吸收、改善肠道功能等。本研究主要对丁酸菌在临床中的应用研究进展进行综述,尤其是对丁酸菌与老年人肠道功能的相关性进行阐述,并展望丁酸菌对老年慢性疾病如糖尿病、心血管疾病、老年痴呆、风湿性疾病及骨质疏松症防治的研究未来。

Butyric acid bacteria is a kind of obligate anaerobic bacilli; butyric acid is the main metabolites of this probotic. Butyric acid bacteria can colonize in human intestine,to some extent has synergistic effect with lactic acid bacteria. It can inhibit the growth of harmful bacteria in the gut,promote the absorption of nutrients,and improve the intestinal function,etc. In this paper we reviewed the advances in the researches on clinical application of butyric acid bacteria,especially expounded the correlation of butyric acid bacteria and intestinal function in the elderly. Some advices were also put forward for further researches on butyric acid bacteria to prevent and control senile chronic diseases such as diabetes,cardiovascular disease,Alzheimer＇s disease,rheumatoid arthritis and osteoporosis.