福建省2013年急性乙型肝炎监测分析

Analysis on acute hepatitis B surveillance in Fujian in 2013

目的分析福建省6个监测点急性乙肝报告的病例资料,评价其实际发病情况。方法对报告的急性病例进行流行病学调查,采集血清进行实验室复核。结果 2013年共报告乙肝4 086例,初始报告急性乙肝692例(16.9%)、慢性乙肝3 373例(82.7%)、未分类21例(0.5%)。经流行病学调查及抗-HBc-IgM 1∶1000检测排除,审核订正后报告急性乙肝269例(6.6%),慢性乙肝3 796例(92.9%),订正后急性乙肝病例占比下降;乙肝发病性别比2.1∶1。抗HBc-IgM估算的急性乙肝发病率明显低于中国疾病预防控制系统报告发病率。结论应提高医务人员对乙肝诊断标准的认识,及时利用实验室检测结果进行乙肝分类诊断,客观评价福建省乙肝发病水平。

Objective To evaluate the actual incidence of acute hepatitis B by analyzing the data from 6 surveillance points in Fujian.Methods The epidemiological investigation was carried out for the reported acute hepatitis B cases and serum samples were collected for laboratory identification. Results Totally 4 086 hepatitis B cases were reported in 2013,692 cases （16.9%） for acute hepatitis B,3 373 cases （82.6%） for chronic cases and 21 cases （0.5%） for not classified in initial report. By the epidemiological investigation and detection of anti-HBc-IgM 1：1000 exclusion, 269 cases of acute hepatitis B （6.6%） and 3 796 chronic cases （92.9%） were reported. After revising, the percentage of acute hepatitis B cases was declined. The case ratio of male to female was 2.1：1. The estimated incidence of acute hepatitis B by anti-HBc-IgM detection was significantly lower than that reported by China information system for diseases control and prevention. Conclusion The awareness level of hepatitis B diagnostic standards of medical staff should be improved, and the classification diagnosis by using laboratory test should be carried out for evaluating the actual incidence level of hepatitis B objectively in Fujian.