子宫肌瘤不同术式对绝经过渡期女性患者卵巢功能、性功能及生活质量的影响

Influence of difference hysteromyoma operations on ovarian function,sexual function and living quality

目的:比较子宫肌瘤不同手术方式对绝经过渡期女性患者卵巢功能、性功能和生活质量的影响。方法:回顾性分析2008年1月至2012年1月于我院确诊的60例子宫肌瘤患者资料,其中30例患者行子宫全切除术(Ⅰ组),另外30例行子宫肌瘤剜除术(Ⅱ组),术后随访24个月。对患者两种手术术后卵巢功能、性生活质量和生活质量等指标进行分析。结果:两组手术均未出现死亡及严重并发症,Ⅱ组患者FSH、LH显著低于Ⅰ组患者(t=4.376和4.112;P=0.018和0.001),E2显著高于后者,差异均具有统计学差异(t=34.981,P=0.021);Ⅱ组患者性功能和生活质量评分显著高于Ⅰ组,差异均具有统计学意义(t=2.785和4.714;P=0.017和0.021)。结论:与子宫全切除术相比,子宫肌瘤剜除术对患者卵巢功能、性功能影响较小,患者生活质量更高,值得临床合理运用。

Objectives： To compare the influence of difference hysteromyoma operations on the ovarian function, sexual function and living quality. Methods： In this study, the data of 60 patients with confirmed hystero- myoma in our hospital from January 2008 to January 2012 were retrospectively analyzed, 30 of who received total hysterectomy （group I） and the others received myoma - enucleationz （ group II） ; all were followed up for 24 months. The ovarian function, sexual function and living quality of patients in both groups were analyzed. Results： There were no mortality and severe complications in the two groups. In group II, the levels of FSH and LH de- creased significantly than patients in group I, with statistically difference （t = 4. 376 and 4. 112; P=0. 018 and 0. 001 ）, while the level of E2 increased significantly, with statistical difference （t = 34. 981, P = 0. 021 ）. Moreo- ver, the sexual function score and living quality score also were significantly higher, with statistical difference （t = 2.785 and 4.714; P = 0. 017 and 0. 021 ）. Conclusion： Compared with total hysterectomy, myoma - enucleationz has less effect on the ovarian and sexual function of patients, hereby enabling a higher living quality, which is wor- thy of clinical application.