中药联合5-氨基酮戊酸光动力疗法和CO_2激光治疗女性尖锐湿疣的疗效观察

Clinical study of Chinese medicine combined with 5-aminolaevulinic acid-based photodynamic therapy and carbon dioxide laser in the treatment of femalecondylomata acuminataon

目的:观察中药联合5-氨基酮戊酸光动力疗法和CO2激光术治疗女性尖锐湿疣患者的临床疗效。方法:80例女性尖锐湿疣患者随机分为两组,对照组行CO2激光术和5-氨基酮戊酸光动力治疗,治疗组在对照组的基础上再联合中药汤剂内服外用治疗。治疗结束后3个月观察疗效和复发率。结果:对照组痊愈率75%,复发率25%;治疗组治愈率92.5%,复发率7.5%,两组痊愈率比较有统计学意义(P<0.05),复发率比较差异亦有统计学意义(P<0.05)。结论:中药联合5-氨基酮戊酸光动力和CO2激光术治疗可提高女性尖锐湿疣患者的临床治愈率,降低其复发率。

Objectives： To observe the clinical effect of Chinese medicine combined with 5 - aminolaevulin- ic acid - based photodynamic therapy and carbon dioxide laser in the treatment of female condylomata aeuminataon. Method： 80 patients were randomly divided into 2 groups, namely control group and treatment group. The control group was treated with 5 - aminolaevulinie acid - based photodynamic therapy and carbon dioxide laser. The treat- ment group was combined with Chinese medicine. The cure rate and recurrence of the two groups were compared 3 months after the treatment respectively. Result： The cure rate and recurrence of the control group were 75% and 25 %, with statistically significant difference （P 〈 0.05 ）. The cure rate and recurrence of the treatment group were 92.5% and 7.5%, with statistically significant difference （ P 〈 0.05）. Conclusion： Chinese medicine combined with 5 - aminolaevulinic acid - based photodynamic therapy and carbon dioxide laser can improve the clinical cure rate and reduce the recurrence in the treatment of female condylomata acuminataon.