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C—erbB-2基因和巨噬细胞移动抑制因子在妇科恶性肿瘤中的研究进展

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摘要 妇科恶性肿瘤和其它恶性肿瘤最基本的特征为局部浸润和远处转移，此特征与新生血管的形成有密切关系。最近的研究中发现C—erbB-2基因和巨噬细胞移动抑制因子（MIF）可促进肿瘤的血管形成，与肿瘤的生长，浸润和转移密切相关。因此联合检测C—erbB-2基因和MIF对妇科恶性肿瘤的诊断和预后有重要的价值。
作者 董秀娟 肖巍 聂瑞雪
机构地区 哈尔滨医科大学第四附属医院妇产科
出处 《中国生育健康杂志》 2014年第6期584-586,共3页 Chinese Journal of Reproductive Health
基金 黑龙江省自然科学基金（H201429）
关键词 C—erbB-2基因 巨噬细胞移动抑制因子 妇科 恶性肿瘤
分类号 R563.8 [医药卫生—呼吸系统]
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参考文献23

  • 1Xu ZH, Ford BD. Uperegulation of eerbB reeepters in rat brain after middle eerebrial arterial occlusion. Neurosci Lett, 2005, 375: 181-186.
  • 2Izumi Y, Xu L, Fukumura D, et al. Tumor biology : hereeptin acts as an anti-angiogenic cocktail. Nature,2002,416:279-280.
  • 3Simeone AM, Li YJ, Breemeling LD, et al. Cyclooxygenase-2 is essential for HER2/neu to suppress N-( 4-hydroxyphenyl ) retinamide apoptotic effects in breast cancer cells. Cancer Res ,2004, 64 : 1224-1228.
  • 4Andersson U, Guo D, Maimer B, et al. Epidermal growth factor receptor family ( EGFR, CerbB-2-4) ingliomas and meningiomas. A eta Neuropatho1,2004,108 : 135 -142.
  • 5Uberall I, Kolar Z, Trojanee R, et al. The status and role of ErbB receptors in human cancer. Exp Mol Patho1,2008,84:79-89.
  • 6Yarden Y ,Sliwkowski MX. Untangling the ErbB signalling network. Nature Reviews Molecular Cell Biology,2001,2 : 127-37.
  • 7Odicino F, Bignotti E, Rossi E, et al. HER-2/neu overexpression and amplification in uterine serous papillary carcinoma: comparative analysis of immunohistochemistry, real-time reverse transcription-polymerase chain reaction,and fluorescence in situ hybridization. Int J Gynecol Cancer,2008,18 : 14-21.
  • 8Bhatavdekar JM, Patel DD, Shah NG, et al. Prognostic significance of immunohistochemicaLly localized biomarkers in stage 1I and stage I breast cancer, a multivariate analysis. Ann Surg Oncol,2000,7:305.
  • 9Perez-Regadera J, Sanchez-Mufioz A, De-la-Cruz J, et al. Negative prognostic impact of the coexpression of epidermal growth factor receptor and c-erbB-2 in locally advanced cervical cancer. Oncology, 2009,76 : 133-141.
  • 10Linforth RA, Anderson NG, Knox WF, et al. CerbB2 nncoprotein expression is increased in breast cancer bone metastases. Endocrine/ Breast ,2001,88:5.

二级参考文献24

  • 1夏晓艾,何成章,李莉华,吕蓓,浦红,任金冬,张振宇,毛玉荣.巨噬细胞移动抑制因子在妇科恶性肿瘤中的表达[J].苏州大学学报（医学版）,2006,26(4):647-649. 被引量：4
  • 2Sun B, NishihimJ, Yoshiki T, et al. Macmphage rnigration inhibitory factor promotes tumor invasion and metastasis via the Rho dependent pathway[J]. Clin Cancer Res, 2005,11 ( 3 ) : 1050- 1058.
  • 3Poon TR,Ng IO,Lau C,et al.Serum vascular endothelial growth factor predicts venous invasion in hepatocellular carcinoma:a prospective study[J].Ann Surg,2001,233(2):227-235.
  • 4Lue H, Klecmann R, Calandra T, et al. Macmphage migration inhibitory factor(MIF):mechanisms of action and role in dis ease[J]. Microbes Infect, 2002,4 (4) : 449-460.
  • 5Kraizer Y, Mawasi N, Seagal J, et al. Vascular endothelial growth factor and angiopoielin in liver regeneration [ J ]. Biochem Biophvs Res Commun, 2001,287 (2) : 209-215.
  • 6Burger-Kentischer A,Goebel H,Seiler R,et al.Expression of macrophage migration inhibitory factor in different stages of human atherosclerosis[J].Circulation,2002,105:1561-1566.
  • 7Nishihira J,Ishibashi T,Fukushima T,et al.Macrophage migration inhibitory factor (MIF):Its potential role in tumor growth and tumor-associated angiogenesis[J].Ann N Y Acad Sci,2003,995:171-182.
  • 8Jeziorska M,Woolley DE.Location neovascularization and cellular composition within vulnerable regions of athetosclerotic plaques of human carotid arteries[J].J Pathol,1999,188:189-196.
  • 9Ross JS,Stagliano NE,Donovan MJ,et al.Atherosclerosis and cancer:Common molecular pathways of disease developmentand progress[J].Ann N Y Acad Sci,2001,947:271-292.
  • 10Bosari S, Delellis RA, Healtley GJ. Microvessel quantitation and prognosis in invasive breast carcinoma [J ]. Hum Pathol, 1992, 23 (4): 755-61.

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中国生育健康杂志
2014年 第6期

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