3Donlan RM,Costerton JW.Biofilms:survival mechanisms of clinically relevant microorganisms[J].Clin Microbiol Rev,2002,15:167-193.
4Walters MC 3rd,Roe F,Bugnicourt A,et al.Contributions of antibiotic penetration,oxygen limitation,and low metabolic activity to tolerance of Pseudomonas aeruginosa biofilms to ciprofloxacin and tobramycin[J].Antimicrob Agents Chemother,2003,47:317-323.
5Xavier JB,Foster KR.Cooperation and conflict in microbial biofilms[J].Proc Natl Acad Sci U S A,2007,104:876-881.
6del Pozo JL,Patel R.The challenge of treating biofilm-associated bacterial infections[J].Clin Pharma col Ther,2007,82:204-209.
7O' Grady NP,Alexander M,Burns LA,et al.Guidelines for the prevention of intravascular catheter-related infections[J].Am J Infect Control,2002,30:476-489.
8Landry DL,Braden GL,Gobeille SL,et al.Emergence of gentamicin-resistant bacteremia in hemodialysis patients receiving gentamicin lock catheter prophylaxis[J].Clin J Am Soc Nephrol,2010,5:1799-1804.
9Doqra GK,Herson H,Hutchison B,et al.Prevention of tunneled hemodialysis catheter-related infections us ing catheter-restricted filling with gentamicin and citrate:a randomized controlled study[J].J Am Soc Nephrol,2002,3:2133-2139.
10Dannenberg C,Bierbach U,Rothe A,et al.Ethanol-lock technique in the treatment of bloodstream infections in pediatric oncology patients with Broviac catheter[J].J Pediatr Hematol Oncol,2003,25:616-621.
2Tagashira Y, Kozai Y, Yamasa H, et,al. A cluster of central line- associated bloodstream infections due to rapidly growing nontuberculous mycobacteria in patients with hematologic disorders at a Japanese tertiary care center: an outbreak investigation and review of the litera tureEJ]. Infect Control Hosp Epidemiol, 2015,36 ( 1 ) .. 76 -80.
