树枝状大分子聚酰胺-胺的合成

Synthesis of Polyamidoamine Dendrimer

以乙二胺(EDA)和丙烯酸甲酯(MA)为原料,采用分步法合成了聚酰胺-胺(PAMAM)树枝状大分子。考察了单体配比、反应温度、反应时间和搅拌速度对半代PAMAM的合成工艺影响。实验结果表明,在n(EDA)∶n(MA)=1∶6时,于25℃下快速搅拌30 h,所得半代PAMAM产率可达92%。

A series of polyamidoamine（ PAMAM） dendrimers were synthesized from ethylenediamine（ EDA） and methyl acrylate（ MA） by the method of stepwise synthesis. The synthesis conditions of half generation of PAMAM dendrimers were optimized by investigating the effects of monomer ratio,reaction temperature and time,and stirring rate on the synthesis process. The experimental results showed that the yield of half generation product was 92% under monomer ratio of EDA to MA 1： 6 and rapid stirring 30 hours at 25 ℃.