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氯胺酮临床抗抑郁作用及其信号传导机制 被引量:1

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摘要 近年来,很多研究发现氯胺酮具有快速起效的抗抑郁作用,其作用可能与AMPA、m TOR、GSK-3等多种分子信号传导通路参与诱导的神经发生、改善突触可塑性、产生抗抑郁效应有关。预期氯胺酮及相关药物的研究有助于今后开发出起效更快、更安全、更有效的抗抑郁药物。
作者 王辉 张志珺
出处 《国际精神病学杂志》 2014年第4期247-249,共3页 Journal Of International Psychiatry
基金 江苏省自然科学基金(BK2012747)
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