饮食与生活方式在糖耐量异常人群中的干预性研究

Diet and lifestyle intervention in populations with impaired glucose tolerance

目的通过饮食调节与生活方式干预观察糖耐量异常人群的整体改善情况。方法对本院健康促进中心进行健康档案管理的81例糖耐量异常者进行观察研究,通过检测干预前后的各项生理指标和生化指标,判断饮食调节与生活方式对糖耐量异常人群的改善作用。结果 81例受试者均完成本次研究,未出现低血糖、严重乏力等不良反应;干预前后体质量指标、腰围、腰臀比、收缩压及舒张压差异均有统计学意义(均<0.05);干预前后总胆固醇、三酰甘油、低密度脂蛋白、空腹血糖及餐后2 h血糖差异均有统计学意义(均<0.05),而高密度脂蛋白干预前后差异无统计学意义(>0.05)。结论建立健康合理的饮食习惯和生活方式对糖耐量异常人群可以起到改善或逆转的作用。

Objective To investigate the improvement situation of impaired glucose tolerance patients by dietary adjustments and lifestyle intervention. Methods Eighty-one patients with impaired glucose tolerance recorded in our health promotion center were observed. Physiological and biochemical indexes before and after the experiment intervention were detected to determine whether dietary adjustment and lifestyle could improve the situation of impaired glucose tolerance. Results Eighty-one subjects completed this study, with no hypoglycemia, severe fatigue and other adverse reactions. Before and after the intervention, body mass index（BMI）, waistline（WL）, waist-hip ratio（WHR）, diastolic blood pressure（DBP）and systolic blood pressure（SBP） differences were statistically significant（ P〈0.05）; differences of triglyceride（TG）, total cholesterol（TC）, low-density lipoprotein（LDL）, Fasting plasma glucose（FPG） and two hours postprandial blood glucose（2 h PG） were statistically significant（P〈0.05）; but HDL was no significantly different（ P〉0.05）. Conclusions It is very important to build a kind of reasonable dietary habits and healthy lifestyle, especially for the impaired glucose tolerance population. It can play a role in improving or reversing.