^(90)Sr-^(90)Y联合洁悠神治疗难治局限性慢性湿疹59例

Strontium-90 combined JUC treated 59 cases of chronic eczema with Limitations and refractory

目的观察90Sr-90Y敷贴联合洁悠神治疗难治局限性慢性湿疹疗效。方法将132例难治性局限性慢性湿疹病例按掷硬币法随机分为两组:研究组59例采用90Sr-90Y敷贴治疗+洁悠神外用治疗;对照组73例接受口服盐酸氮卓斯汀片+外涂复方氟米松软膏治疗。结果研究组治愈率49.2%,有效率83.1%,对照组治愈率21.9%和有效率68.5%,研究组疗效优于对照组(P<0.05);研究组无效率16.9%,低于对照组31.5%(P<0.05);研究组复发率10.3%;远低于对照组50.0%(P<0.05);研究组副反应发生率5.1%,与对照组5.5%相近,差异无统计学意义(P>0.05)。结论针对顽固难治的局限性慢性湿疹,采用90Sr-90Y敷贴联合洁悠神治疗不失为一种较好的选择。

[ Objective ] To observe the efficacy of ^90Sr combined JUC treated chronic eczema with refractory and limitations. [Methods] 132 cases of chronic eczema with refractory and limitations were randomly divided into two groups by a coin toss method： Observer group （59 cases） received strontium-90＋JUC treatment; Control group （73 cases） receivied azelastine hydrochloride＋coated compound flumetasone ointment. [ Results ] Observation group＇s the cure rate was 49.2%, the efficiency rate was 83.1%; The control grou＇s the cure rate and the efficiency rate were 21.9% and 68.5%, The efficacy of the observation group was better than the control group （P 〈0.05）; Observation group＇s in efficiency rate was 10.3%, lower than the control group＇s 31.5%（P 〈0.05）; Observation group＇s the recurrence rate was 7.1%, lower than the control group＇s 50.0% （P 〈0.05）; The observation group＇s incidence side effects was 5.1%, similar with the control group＇s 5.5%, the difference was not statistically significant （P 〉0.05）. [ Conclusion ] It was a better choice that ^90Sr combined with applicator therapy for chronic eczema of refractory and limitations.