摘要
目的分析影响慢性阻塞性肺疾病急性加重期(AECOPD)住院患者病情恶化的危险因素。方法分析199例AECOPD住院患者,按病性转归分为缓解组和恶化组,采用单因素与多因素分析方法比较两组临床指标。结果 AECOPD恶化发生率为10.55%,病情恶化与血清白蛋白<30 g/L(P<0.05)、合并肺炎(P<0.05)密切相关。结论低蛋白血症、合并肺炎是影响AECOPD住院患者病情转归的独立危险因素。
Objective To investigate the risk factors of deterioration in hospitalized patients with AECOPD in pneumology department. Methods 199 cases of hospitalized patients with AECOPD were divided to the remissive group and the deteriorative group according to their outcomes. The clinical indexes of the two groups were compared by univariate and multivariate analysis. Results The rate of deterioration was 10. 20%. Deterioration was closely associated with serum-albumin 〈30 g/L （ OR = 9. 977, 95% CI： 0. 694 - 0. 918, P 〈 0. 05 ）, pneumonia （ OR = 4. 077, 95 % CI： 1. 035 - 10. 048, P 〈 0. 05）. Conclusion Hypoproteinemia and pneumonia are independent risk factors of deterioration of AECOPD.
出处
《临床肺科杂志》
2015年第1期4-6,共3页
Journal of Clinical Pulmonary Medicine
关键词
慢性阻塞性肺疾病
恶化
危险因素
chronic obstructive pulmonary disease
deterioration
risk factor
