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血清C-反应蛋白和红细胞分布宽度在AECOPD与稳定期的变化及意义 被引量:12

Changes and implications of CRP and RDW in exacerbation and stable phases of COPD
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摘要 目的观察慢性阻塞性肺疾病(COPD)患者急性加重期入院、出院时血清C-反应蛋白(CRP)和红细胞分布宽度(RDW)与正常人的差异。方法分别检测健康老年组(年龄≥65岁)、COPD急性加重期患者入院、出院时CRP和RDW水平,比较组间各指标的差异。结果急性加重期患者入院、出院时CRP和RDW水平均高于健康老年组,入院时CRP水平高于出院时(P<0.01),入院、出院时RDW水平无统计学差异。结论 CRP和RDW可一定程度评估COPD病情及反映病情变化。 Objective To investigate the changes of serum level of C-reactive protein (CRP) and red cell distribution width (RDW) in exacerbation and stable phases of chronic obstructive pulmonary disease (COPD). Methods The levels of CRP and RDW were detected and analyzed in the elderly healthy controls and the COPD group. Results The levels of CRP and RDW in patients with AECOPD were higher than that of the healthy controls, and the level of CRP was higher on admission than discharge in AECOPD patients (P 〈 0. 01 ). There was no significant difference in RDW before and after the treatment in COPD group. Conclusion CRP and RDW can be used to assess the severity of COPD, as well as indicate the clinical conditions.
出处 《临床肺科杂志》 2015年第1期16-18,共3页 Journal of Clinical Pulmonary Medicine
关键词 慢性阻塞性肺疾病 C-反应蛋白 红细胞分布宽度 Chronic obstructive pulmonary disease C-reactive protein red cell distribution width
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