匹多莫德佐治儿童难治性肺炎支原体肺炎疗效观察

Clinical observation of Pidotimod in the treatment of children with refractory mycoplasma pneumoniae pneumonia

目的观察匹多莫德佐治儿童难治性肺炎支原体肺炎(Refractory Mycoplasma pneumoniae pneumonia,RMPP)的临床疗效。方法将86例RMPP患儿随机分为治疗组和对照组各43例,对照组予对症等常规治疗,治疗组在常规治疗的基础上加用匹多莫德,回顾性分析两组的临床疗效。结果治疗组总有效率(90.70%)优于对照组(65.12%),差异有明显的统计学意义(P<0.01);其中发热及咳嗽等症状、体征和影像学异常的消退时间均较对照组缩短,1年内疾病复发次数少于对照组,两组比较差异均有统计学意义(P<0.05)。结论匹多莫德佐治儿童RMPP有明显疗效,并可减少复发。

Objective To observe the clinical curative effect of Pidotimod in the treatment of children with refractory mycoplasma pneumoniae pneumonia （RMPP）. Methods 86 children with RMPP were randomly divided into the treatment group and the control group with 43 cases in each group. The control group received conventional treatment of symptomatic, and the treatment group was treated with Pidotimod based on routine treatment. The curative effect was retrospectively analyzed. Results The total effective rate of the treatment group was 90.70%, which was higher than that of the control group （65.12%）. The regression time of fever and cough symptoms was shorter in the treatment group than in the eontrol group. The recurrence within 1 year was less in the treatment group than in the control group （ P 〈 0. 05 ）. Conclusion Pidotimod has obvious curative effect and can reduce the recurrence in the treatment of children with RMPP.