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芬太尼联合咪达唑仑对ICU复合型外伤患者机械通气镇静效果的疗效观察 被引量:3

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摘要 目的:探讨ICU复合型外伤机械通气患者采用芬太尼联合咪达唑仑镇静的效果。方法:收集我院ICU复合型外伤采用机械通气治疗患者60例,随机分为观察组和对照组,各30例,均给予诱导量咪达唑仑0.08~0.33mg/kg静推,观察组给予咪达唑仑0.05~0.1mg/(kg·h)联合芬太尼0.5~1μg/(kg·h)微量泵注入维持,对照组给予咪达唑仑0.08~0.2mg/(kg·h)微量泵注入维持。观察两组镇静镇痛前后血压、心率、呼吸、血气分析、镇静镇痛评分(Ramsay评分)及停药苏醒后配合治疗时间的变化。结果:两组患者均在镇静后2h出现血压下降,心率、呼吸、血气分析均好转,比较无统计学差异。观察至72h镇静满意度,机械通气至停药苏醒后配合机械通气治疗时间观察组短于对照组,两组间比较差异有统计学意义(P〈0.05)。结论:芬太尼联合咪达唑仑对ICU复合型外伤患者机械通气镇静效果比单用咪达唑仑好,且镇静用药时间缩短,对减少并发症早日脱机有力,值得在ICU推广。
作者 刘杰
出处 《医学理论与实践》 2014年第19期2591-2592,共2页 The Journal of Medical Theory and Practice
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