摘要
目的探讨帕金森病膀胱尿道功能障碍的危险因素，为预防及早期干预活动提供理论依据。方法选取浙江省人民医院2012年9月-2013年10月在神经内科门诊就诊和住院的209例帕金森病患者为研究对象，将209名患者随机分为膀胱尿道功能障碍组和排尿正常组，分析患者的一般情况、病情严重程度、病程及伴发自主神经症状与其尿道功能的关系，单因素分析采用，检验，多因素分析使用Logistic回归分析。结果单因素分析结果表明高龄、吸烟及病情重的患者易发生膀胱功能障碍（P〈0．05），文化程度低的患者易发生膀胱尿道功能障碍（P〈0．05），伴发的自主神经症状与膀胱尿道功能障碍相关（P〈0．05），而饮酒、喝茶、高血压及病程长短与之无关（P〉0．05）；Logistic多元回归分析表明高龄（OR=3．43）、吸烟（OR=2．76）及病情重（OR=5．29）是膀胱尿道功能障碍危险因素，文化程度高是（OR=0．49）膀胱尿道功能障碍保护因素。结论高龄、吸烟及病情重是帕金森病膀胱尿道功能障碍发生的危险因素，伴发的自主神经症状是其发生的相关因素，饮酒、喝茶、高血压及病程与之无关，文化程度高是其保护因素。
Objective To investigate the risk factors for Parkinson＇ s patients complicated with urethra bladder dysfunction, and provide theoretical basis for prevention and early intervention. Methods Selection of Zhejiang province people＇ s hospital between September 2012 and October 2013 in neurology treatment of 209 patients with Parkinson＇ s disease as the research object, were randomly divided into the bladder dysfunction group and normal urination. Research content includes the patient＇ s general condition, disease severity, duration, and concomi- tant autonomic nervous symptoms, single factor analysis of the X2 test, multiple factors analysis by Logistic regression analysis. Results ： The single factor analysis showed that age, smoking, low degree of the disease is severe, culture of easily occurs in patients with bladder dysfunction, with symptoms of autonomic nerve is the occurrence of related factors, alcohol, tea, high blood pressure has nothing to do with the course of the disease. Multiple regression analysis showed that age, smoking and severe disease are the risk factors for bladder dysfunction, high degree of culture is the protection factor of bladder dysfunction. Conclusion Age, smoking and severe disease are the risk factors for Parkinson＇ s patients complicated with urethra bladder dysfunction, symptoms of autonomic nerve is the occurrence of related factors, alcohol, tea, high blood pressure has nothing to do with the course of the disease, the high degree of culture is its protection factors.
