坦索罗辛在预防术后尿潴留中的作用

The effect of tamsulosin on prevention the urinary retention after operation

目的 探讨坦索罗辛在预防术后尿潴留中的临床价值.方法 收集2012年8月～2013年7月在我院椎管内麻醉下行曲张精索静脉切除术、腹股沟疝修补术及阴囊手术的男性患者116例作为研究对象,年龄18～50岁.将患者随机分为两组：坦索罗辛组59例,于术前14、2小时及术后10小时给予坦索罗辛0.4mg;安慰剂组57例,于术前14、2小时及术后10小时给予安慰剂.观察患者术后24小时是否出现尿潴留、排尿困难及其他副作用.结果 坦索罗辛组患者术后尿潴留发生率（5.9％）远小于安慰剂组（21.1％）,手术时间及年龄也与术后尿潴留有关,两组患者均无严重不良反应.结论 术前给予坦索罗辛治疗可以减少曲张精索静脉切除术、腹股沟疝修补术及阴囊手术术后尿潴留及术后留置导尿管的发生率.

Objective To investigate the clinical value of tamsulosin in prevention the urinary retention after operation.Methods 116 patients with spinal canal anesthesia downlink varicose spermatic vein resection,inguinal hernia repair and male scrotum surgery were collected continuously and selected as the research object.They were on ages 18to50 years old.Patients were randomly divided into two groups：tamsulosin group（59cases）with tamsulosin for a 0.4mg14 h,2hin the preoperative and postoperative 10 hand the placebo group（57cases）with placebo 14 h,2hbefore operation and postoperative 10 h.The urinary retention,dysuria and other side effects were observed.Results Postoperative incidence of urinary retention（5.9%）of patients in tamsulosin group was far less than the postoperative incidence of urinary retention（21.1%）of patients in placebo group.The operation time and age are also associated with postoperative urinary retention,and two groups of patients had no serious adverse reactions.Conclusion Preoperative giving tamsulosin for treatment can reduce varicose spermatic vein resection,postoperative urinary retention after inguinal hernia repair and scrotum and the incidence of postoperative urethral catheter.