我院2011-2013年临床药师参与300例患儿应用抗菌药物会诊分析

Analysis of Clinical Pharmacists Participating in 300 Cases of Children Antibacterial Drugs Consultation in Our Hospital during 2011-2013

目的:了解临床药师参与会诊的落实情况和结果,为临床药师更好地参与临床工作提供依据。方法:对2011-2013年我院临床药师参与300例16岁以下患儿临床感染疾病的会诊情况,包括申请会诊目的及内容、会诊模式、肝肾功能、会诊科室、菌群分布、会诊建议是否采纳、治疗转归、使用前5位的抗菌药物、非肝肾受损不良反应等进行统计分析。结果:申请会诊科室中以儿科普通病区最多(45.33%,136/300),其次为儿科重症病区(PICU);申请会诊目的以指导选择、调整抗菌药物为主(87.67%,263/300);会诊建议被全部采纳的有253例(占84.30%),部分采纳的有28例(占9.33%),未采纳的有19例(占6.33%)。意见采纳后再行治疗,痊愈50例(占16.66%),好转127例(占42.33%),效果不明显71例(占23.66%),其他33例(占11.00%)。结论:临床药师会诊已经成为临床治疗工作的一部分,在感染疾病治疗中起到了积极作用。

OBJECTIVE： To probe into the practice and results of clinical pharmacists participating in consultations so as to provide reference for clinical pharmacists participating in clinical practice in the future. METHODS ： The pratice of clinical pharma- cists participating in 300 cases of clinical consultation for the children under 16 years-old with infection disease during 2011- 2013 were analyzed statistically in following aspects： purpose and contents for consultation, consultation mode, hepatorenal function, the departments of consultation, pathogens distribution, the acceptance of consultative suggestions, treatment outcome, top 5 antbi- bacterial drugs, non-hepatorenal ADR, etc. RESULTS： Most consultation occurred in wards of general pediatrics （45.33 %, 136/ 300）, followed by pediatric intensive care unit （PICU）. The main purpose was to adjust or guide the use of antibacterial drugs （87.67%, 263/300）. A total of 253 cases of consultation comments （84.30%） were adopted completely, 28 cases （9.33%） were adopted partly, and 19 cases （6.33 % ） were refused. After the acceptation of consultations, 50 patients were cured （ 16.66 % ）, 127 were improved （42.33%）, 71 were invalid （23.66%）, and the others were 33 cases （11.00%）. CONCLUSIONS： The participa- tion of clinical pharmacists in consultation has became a part of medical treatment, and plays an important active role in the treat- ment of infection disease.