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替吉奥胶囊治疗老年晚期胃癌的疗效评价 被引量:3

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摘要 胃癌患者中老年患者居多,50%的胃癌患者明确诊断时已出现转移,无法进行手术根治处理,即使能够手术的患者,术后也有多数患者出现周围及远处转移。目前,对于老年晚期胃癌的治疗仍是以化疗为主的综合治疗,临床上常用的抗肿瘤药物主要有铂类、氟尿嘧啶、阿霉素类等,对于老年患者消化道反应、骨髓抑制均较重,单药有效率17%~30%不等。
出处 《肿瘤基础与临床》 2014年第5期416-417,共2页 journal of basic and clinical oncology
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  • 1黄河,管忠震,秦凤展,张燕军,黎莉,高亚杰,王顺金,顾康生,郭颖,孙飘扬.左亚叶酸钙联合5-氟尿嘧啶、奥沙利铂治疗晚期或复发胃、结直肠癌的Ⅱ期临床研究[J].广东医学,2005,26(11):1568-1570. 被引量:10
  • 2Malet-Martino M,Martino R.Clinical studies of three oral prodrugs of 5-fluorouracil (capecitabine,UFT,S-1):a review[J].Oncologist,2002,7(4):288-323.
  • 3Tanaka F,Fukuse T,Wada H,et al.The history,mechanism and clinical use of oral 5-fluorouracil derivative chemotherapeutic agents[J].Curr Pharm Biotechnol,2000,1(2):137-164.
  • 4Shirasaka T,Shimamato Y,Ohshimo H,et al.Development of a novel form of an oral 5-fluorouracil derivative (S-1) directed to the potentiation of the tumor selective cytotoxicity of 5-fluorouracil by two biochemical modulators[J].Anticancer Drugs,1996,7(5):548-557.
  • 5Shirasaka T,Tsukuda M,Inuyama Y,et al.New oral anticancer drug,TS-1 (S-1)-from bench to clinic[J].Gan To Kagaku Ryoho,2001,28(6):855-864.
  • 6Sato A,Ito T,Tomita T,et al.Chemotherapy of gastric cancer--a review of clinical trials in Japan[J].Gan To Kagaku Ryoho,2002,29(9):1522-1531.
  • 7Shirasaka T. New oral anticancer drug, ( TS - 1 ) - from bench to clinic [J]. Gan To Kagaku Ryoho,2001.
  • 8Koizumi W. S - 1 plus cisplatin versus S - 1 alone for first - line treatment of advanced gastric cancer ( SPIRITS trial) :a phase. Ⅲ trial[J]. Lancel Oncol,2008.
  • 9Takahashi I. S - 1 in the treatment of advanced and recurrent gastric cancercurrent state and future prospects [ J ]. GASTRIC CANCER,2003.
  • 10Boku N. Chemotherapy for metastatic disease:review from JCOG trials [ J ]. International Journal of Clinical Oncology ,2008.

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