丹参多酚酸盐对不稳定型心绞痛的临床研究

Clinical Research of Salvianola in the Treatment of Unstable Angina Pectoris

目的:观察丹参多酚酸盐治疗不稳定型心绞痛的临床疗效。方法:按照随机数字表法将64例患者分为治疗组和对照组,对照组仅常规药物治疗,治疗组在常规药物治疗基础上加用丹参多酚酸盐,比较两种治疗方案对疗效、含服的硝酸甘油量的变化及心电图的影响。结果:治疗组临床总有效率为88.9%,心电图总有效率为83.3%,含服的硝酸甘油量的停减率为77.8%;对照组依次为64.3%、60.7%和53.6%,两组比较差异有统计学意义(P<0.05)。结论:在常规药物治疗基础上加用丹参多酚酸盐治疗不稳定型心绞痛能取得更满意的临床效果。

Objective：To explore the effect of Salvianola in the treatment of unstable angina pectoris.Method：Sixty-four patients with coronary heart disease were randomly divided into the treatment group and the control group.The treatment group was given regular drugs and Salvianola in the meanwhile,whereas the control group was only given regular drugs.The therapeutic effect was analyzed by the symptom,the amount of glycerin trinitrate for sublingual use and electrocardiograph.Result：Compared with the control group,there was significant increase in the effect rate indicated by the symptoms（88.9%vs 64.3%,P〈0.05）,the rate of decreasing amount of glycerin trinitrate for sublingual use or withdrawal（77.8%vs 53.6%,P〈0.05）, and the effect rate indicated by electrodiogram（83.3%vs 60.7%,P〈0.05）.Conclusion：Salvianola combination with regular drugs could achieve better therapeutic effect in the treatment of unstable angina pectoris.