早期应用参麦注射液并复方丹参注射液治疗急性心肌梗死对患者血清肌钙蛋白I水平的影响

Effect Study of Early Using Shenmai Injection and Fufang Danshen Injection on Cardiac Troponin I( cTNI) of Acute Myocardial Infarction(AMI) Patients

目的:观察参麦注射液并复方丹参注射液联合治疗急性心肌梗死(AMI)经溶栓治疗后患者血清肌钙蛋白I(c Tn I)的影响,分析二者对心肌的保护作用。方法:筛选我科急诊AMI病患者60例,随机分为研究组和对照组,每组30例,两组患者均接受常规急诊治疗,研究组在常规急诊溶栓治疗的基础上加用参麦注射液60 m L,每日1次,复方丹参注射液20 m L,每日1次,两药均连用7日。检测两组患者入院时、治疗后24 h和72 h血清肌钙蛋白I(c Tn I),观察两组临床疗效。结果:经治疗,两组患者AMI症状较治疗前均有好转,研究组与对照组总有效率分别为86.67%和53.33%,比较差异具有统计学意义(P<0.05),治疗24 h和72 h,研究组患者c Tn I水平均较对照组低(P<0.05)。结论:参麦注射液和丹红注射液可有效保护心肌细胞,早期应用可降低AMI患者c Tn I水平,改善患者预后。

Objective：To observe the effect of Shenmai Injection and Fnfang Danshen Injection on cardiac troponin I （cTnI）of a- cute myocardial infarction（AMI） patients after thrombolytic therapy. Methods ：60 cases of emergency AMI patients in our hospital were randomly divided into study group and control group and each group had 30 cases. All patients received routine emergency treatment and the patients of study group accepted 60mL Shenmai Injection （qd） and 4mL Fnfang Danshen Injection （qd） on the basic treatment. The cTnI of two groups 24 h and 72 h after treatment was tested. Results ：After treatment ,symptoms of two groups＇ patients were all better. Total effective rates of study group and control group were respectively 86.67% and 53.33% and there was significant difference between the two groups （P 〈 0. 05）. Serum level of cTnl of study group was lower than that of control group 24 h and 72 h after treatment （P 〈 0. 05 ）. Conclusion：Shenmai Injection and Fnfang Danshen Injection could effectively protect the myocardium and decrease serum level of cTnI in early period of treatment about AMI so as to improve the prognosis of patients.