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水相中锡粉促进醛的烯丙基化反应研究

Study on the allylation of aldehydes promoted by Sn in water
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摘要 以锡粉、醛和烯丙基溴为原料,二氯甲烷-水作为混合溶剂,通过锡粉促进醛的烯丙基化反应,合成了一系列高烯丙基醇.此方法具有反应条件温和、操作简单、产率高、避免使用有毒的有机锡试剂等优点,为高烯丙基醇类化合物的合成提供了一种简单易行的方法. This paper studied the allylic reaction of aldehydes promoted by tin powder using methylene chloride-water as co-solvent at room temperature, and successfully synthesized a series of homoallylic alcohols.This method has the advantages of simple operation,mild reaction conditions,high yields,and avoiding the use of toxic organotin. It provides a simple and convenient method for the synthesis of homoallylic alcohols.
作者 王克虎 刘宾年 牛玉卓 黄丹凤 胡雨来
机构地区 甘肃省高分子材料重点实验室、西北师范大学化学化工学院
出处 《西北师范大学学报（自然科学版）》 CAS 北大核心 2014年第6期54-58,共5页 Journal of Northwest Normal University(Natural Science)
基金 国家自然科学基金资助项目(21262031)
关键词 一锅法 高烯丙基醇 锡粉 one-pot homoallylic alcohols tin powder
分类号 O621.3 [理学—有机化学]
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参考文献11

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西北师范大学学报（自然科学版）
2014年 第6期

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