医院2010年至2012年抗精神病药物利用分析

Use Situation of Antipsychotic Drugs in Our Hospital from 2010 to 2012

目的了解医院2010年至2012年抗精神病药物的使用现状,为临床合理用药提供依据。方法根据医院药库信息管理系统提供的数据,采用世界卫生组织(WHO)推荐的限定日剂量(DDD)为指标的分析方法,根据购药金额,通过用药频度(DDDs)、限定日费用(DDC)、药物利用指数(DUI)的计算和排序,对医院抗精神病药物的使用进行分析。结果 2010年至2012年购药总金额呈逐年上升趋势。DDDs排在前4位的是非典型抗精神病药物,DDC排在前4位的是非典型抗精神病药物。非典型抗精神病药物中大多数DUI<1,典型抗精神病药物中大多数DUI>1。结论该院非典型抗精神病药物的使用占主导,符合抗精神病药物的使用发展趋势。

Objective To investigate the current use situation of the antipsychotic drugs in our hospital from 2010 to 2012 to provide the basis for clinical rational drug use. Methods According to the data provided by the hospital drug storehouse information manage- ment system and by adopting the defined daily dose（DDD） analysis method recommended by WHO,the use of the autipsychotic drugs in our hospital were analyzed by using the amount of money for purchasing drugs,DDDs,defined daily cost（DDC）,calculating and rank- ing the drug utilization index（DUI）. Results The total amount of money for purchasing drugs showed an increasing trend from 2010 to 2012. The top four drugs in DDDs were the atypical antipsychotic drugs and the top four drugs in DDC were the atypical autipsychotic drugs. Most of atypical antipsychotic drugs had DUI 〈 1 and most of typical antipsychotic drugs had DUI 〉 1. Conclusion The use of the atypical antipsychotic drugs is dominant,which conforms to the development trend in the use of antipsychotic drugs.