丹红注射液联合前列地尔治疗老年腔隙性脑梗死58例

Clinical Efficacy of Danhong Injection Combined with Alprostadil in Treating Senile Lacunar Infarction in 58 Cases

目的观察丹红注射液联合前列地尔治疗老年腔隙性脑梗死的临床疗效。方法将116例老年腔隙性脑梗死患者随机分为对照组和治疗组,各58例。两组患者均采用丹红注射液治疗,治疗组患者加用前列地尔,15 d为1个疗程,服用2个疗程后对比两组患者的临床效果。结果治疗组患者的总有效率为93.10%,明显高于对照组的70.70%(P<0.05)。两组患者均未出现不良反应;两组患者的日常生活活动能力量表(ADL)与简易智能量表(MMSE)的评分存在显著差异(P<0.05)。结论丹红注射液联合前列地尔治疗老年腔隙性脑梗死疗效显著,并发症少,安全性较高,值得临床推广。

Objective To observe the clinical effect of Danhong Injection combined with alprostadil in treating senile lacunar infarc-tion. Methods 116 patients with senile lacunar infarction were randomly divided into the control group and the treatment group,58 cases in each group. The two groups were treated by Danhong Injection,while the treatment group was added with alprostadil. 15 d were a course of treatment. The clinical effects after 2 courses of treatment were compared between the two groups. Results The total effec-tive rate was 93. 10% in the treatment group,which was significantly higher than 70. 70% in the control group（ P 〈 0. 05）. No adverse reactions occurred during treatment in the two groups. The scores of the activities of daily living（ADL） and the mini mental state ex-amination（MMSE） had significantly differences between the two groups（ P 〈 0. 05）. Conclusion Danhong injection combined with al-prostadil in treating senile lacunar infarction has significantly clinical efficacy,little complications and high safety,which is worthy of clinical promotion.