摘要
设计合成一种全新的苯硫酚检测探针。以试卤灵钠为主要原料，在三乙胺催化下与2，4-二硝基氯苯合成了7-（2’，4’-二硝基苯氧基）-3H-吩噁嗪-3-酮，产率为41．7％。在pH7．4的磷酸盐缓冲溶液中，该化合物能与苯硫酚发生亲核取代反应，反应体系在可见光区2=580nm处有强吸收。该探针测定苯硫酚的线性范围为0．1-20μmol／L，检出限为8．9×10^-8mol／L，精密度为3．7％（n=8），回收率为106％。该方法可快速检测环境及生物体中的苯硫酚。
A kind of brand-new thiophenoldetection probe was designed and synthesised. 7-Hydroxy-3H-phenoxazin- 3-one sodium salt as main materials, catalyzed in triethylamine, a new chemodosimeter 7-（2＇ ,4＇ -dinitrophenoxy）-3H- phenoxazin-3-one was synthetized to determine thiophenol, the yield was 41.7%. It showed that in pH 7.4 phosphate buffer solution, the compound could be reacted with thiophenol, the reaction system had a strong absorption in the visible region of 580 nm, the absorbance increase was linearly with thiophenol concentration from 0.1μmol / L to 20 μmol / L with a detection limit of 8.9 × 10^-8 mol/L. The precision was 3.7%（n=8）, and the recovery rate was 106%. This method provides an effective means for the detection of environmentand organisms of thiophenol.
出处
《化学分析计量》
CAS
2014年第6期85-87,共3页
Chemical Analysis And Meterage
