饮用水中卤乙腈的形成和毒性研究进展

Formation and toxicity of haloacetonitriles in drinking water:a review of recent studies

卤乙腈(HANs)是饮用水消毒过程中产生的一类含氮消毒副产物,较受控消毒副产物具有更强的细胞毒性和遗传毒性,还存在致畸性。人群长期经饮用水暴露HANs可能增加健康风险。故该文综述了饮用水中卤乙腈的形成、细胞毒性、遗传毒性、致癌性和生殖发育毒性等方面的研究进展,以期为今后饮用水中卤乙腈的管控和标准限值制定提供参考。

Haloacetonitriles（HANs） is a nitrogenous disinfection by-products formed during the disinfection of drinking water and it had stronger cytotoxicity and genotoxicity than regulated disinfection by-products, moreover,it also had teratogenicity.Long-term exposure to HANs may increase health risks,so the research progress of the formation,cytotoxicity,genotoxicity,carcinogenicity,reproductive and developmental toxicity of HANs were summarized to provide a reference for controlling HANs in drinking water and establishing the standard of drinking water quality in the future.