高压氧早期治疗地震脊髓损伤的疗效观察

Observation on the therapeutic effect of early hyperbaric oxygen treatment on spinal cord injury inflicted in the earthquake

目的 观察高压氧（HBO）早期综合治疗对脊髓损伤地震伤员的疗效.方法 经患者及家属知情同意,按数字表法随机将32例脊髓损伤患者分为高压氧治疗组（HBO组,18例）和常规治疗组（常规组,14例）.采用脊髓损伤ASIA2000分级法对2组患者术后2d内及HBO治疗3个疗程后分别进行分级评分,比较HBO和常规治疗后ASIA分级评分的变化.结果 （1）2组患者在治疗前各项ASIA评分差异不具有统计学意义（P＞0.05）,治疗后2组患者各自的感觉和运动平面评分均高于治疗前,差异有统计学意义（P＜0.05）.（2）HBO组治疗后的感觉（169.50±6.74）和运动（77.78±5.25）平面评分高于常规组治疗后的评分（分别为162.00±7.43和70.86±4.59）,且差异有统计学意义（P＜0.05）.（3）损伤分级在各组之间的差异无统计学意义（P＞0.05）.结论 HBO早期治疗对脊髓损伤地震伤员具有明显疗效,有助于患者感觉和运动平面的恢复.

Objective To observe the therapeutic effect of early comprehensive HBO treatment on spinal cord injury inflicted in the earthquake.Methods With the knowledge and consent of the patients and dependants,32 spinal cord injury patients were randomly divided into the hyperbaric oxygen group （the HBO group） and the routine therapy group.The ASIA2000 classification system of spinal cord injury was applied to identify the grades of the groups of patients,2 days after surgery and following 3 courses of HBO treatment.Then,changes in ASIA classification scores after the HBO and routine treatment were compared between the 2 groups.Results （1）No statistical significance could be seen in all the ASIA scores before treatment in both groups（P ＞ 0.05）.However,sensory and motor plane scores for the patients of both groups were all higher than those before treatment,with statistical significance （P ＜ 0.05）.（2） For the patients in the HBO group,sensory and motor plane scores after treatment were higher than those of the routine therapy group,also with statistical significance （P ＜ 0.05）.（3） No statistical significance could be noticed in the injury classification,when comparisons were made between the groups （P ＞ 0.05）.Conclusions Early HBO treatment had obvious therapeutic effect on spinal cord injury inflicted in the earthquake,and could help the recovery of the sensory and motor plane of those patients.