熵权TOPSIS模型在甘肃产当归药材综合质量评价中的应用

Application of Entropy-Weight TOPSIS Model in Synthetical Quality Evaluation of Angelica sinensis Growing in Gansu Province

目的:以甘肃产当归药材的综合质量评价为例,探讨中药综合质量评价的熵权TOPSIS模型的建立与应用。方法:以当归药材中阿魏酸、正丁基苯酞、正丁烯基苯酞、Z-藁本内酯、亚油酸、挥发油以及醇溶性浸出物含量为评价指标集,通过信息熵法确定各评价指标的权重,建立基于熵权的TOPSIS评价模型,利用最优解的欧氏贴近度综合评价甘肃产当归药材质量。结果:基于该模型的评价结果符合当归药材的道地性内涵及临床用药经验的认知。结论:该评价模型计算简便、客观可靠,可推广应用于中药综合质量评价。

Objective： To investigate the establishment and application methods of entropy-weight TOPSIS model in synthetical quality evaluation of traditional Chinese medicine with Angelica sinensis growing in Gansu Province as an example. Methods： The contents of ferulic acid,3-butylphthalide,Z-butylidenephthalide,Z-ligustilide,linolic acid,volatile oil,and ethanol soluble extractive were used as an evaluation index set. The weights of each evaluation index were determined by information entropy method. The entropyweight TOPSIS model was established to synthetically evaluate the quality of Angelica sinensis growing in Gansu Province by Euclid closeness degree. Results： The results based on established model were in line with the daodi meaning and the knowledge of clinical experience. Conclusion： The established model was simple in calculation,objective,reliable,and can be applied to synthetical quality evaluation of traditional Chinese medicine.