钛铝金属间化合物膜对中药提取液的精制研究

Ti-Al Intermetallic Compound Membrane Refining Chinese Medicinal Materials Extract

目的:对钛铝金属间化合物膜精制中药提取液的效果进行初步评价。方法:用钛铝金属间化合物膜对莲子心、杜仲叶和中药复方白花三地(地锦草、两面针、地骨皮、白花蛇舌草)的提取液进行过滤,对提取液过滤前后在总固体、指标成分等方面的变化进行对比分析。结果:通过30和10μm孔径两级过滤后,莲子心总固体去除率分别为1.2%和22.66%,甲基莲心碱保留率分别为97.56%和95.12%;杜仲叶的总固体去除率分别为1.2%和22.66%,绿原酸保留率分别为95.45%和87.28%;中药复方白花三地总固体去除率分别为11.09%和14.29%,槲皮素保留率分别为98.58%和95.43%。结论:钛铝金属间化合物膜过滤精制技术对中药提取液具有较好的精制效果。

Objective： To preliminarily evaluate the refining effect on Chinese medicinal materials extract using the microfiltration membrane of Ti-Al intermetallic compound. Methods： Conduct a series of microfiltration experiments on the extract of several commonly used Chinese medicinal materials（ Nelumubinis Plumula and Eucommiae Folium） and compound preparation of Baihuasandi. Then,analyze the changes of traits,total solid and index components before and after filtring. Results： After two stages（ 10 μm and 30 μm） of membrane micro-filtring,the total solid removal rates of Nelumubinis Plumula were 1. 2% and 22. 66%,and the remaining rates of neferine were 97. 56% and 95. 12%; The total solid removal rates of Eucommiae Folium were 1. 2% and 22. 66%,and the remaining rates of caffeotannic acid were 95. 50% and 87. 28%; The total solid removal rates of Baihuasandi were 11. 09% and 14. 29%,and the remaining rates of quercetin were 98. 58% and 95. 43%,respectively. Conclusion： Microfiltration membrane technique utilizing the Ti-Al intermetallic compound has a good effect in refining Chinese medicinal materials extract.