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宫颈环形电切术联合干扰素治疗宫颈上皮内瘤变的临床疗效研究 被引量:8

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摘要 目的研究宫颈环形电切术联合干扰素治疗宫颈上皮内瘤变的临床疗效。方法 130例宫颈上皮内瘤变患者随机分为观察组和对照组,各65例。观察组患者接受宫颈环形电切术联合干扰素治疗,对照组患者接受宫颈环形电切术,比较两组患者的术后复发率以及免疫功能。结果术后1、2、3年随访发现观察组患者的复发率低于对照组,差异具有统计学意义(P<0.05);观察组患者的Th1类细胞因子肿瘤坏死因子-α(TNF-α)、干扰素-γ(IFN-γ)含量高于对照组,Th2类细胞因子白细胞介素-6(IL-6)、白细胞介素-10(IL-10)含量低于对照组;差异有统计学意义(P<0.05)。结论宫颈环形电切术联合干扰素治疗有助于预防疾病复发、改善免疫功能,是治疗宫颈上皮内瘤变的理想方法。
作者 于红波
出处 《中国现代药物应用》 2014年第24期87-88,共2页 Chinese Journal of Modern Drug Application
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