老年性黄斑变性危险因素研究进展

Research advance on risk factors of age-related macular degeneration

年龄相关性黄斑变性(ARMD)是随着年龄增长出现的一种退行性疾病。在西方国家是50岁以上人群不可逆失明的最常见原因,在我国其患病率也在逐年增加。但是,到目前为止仍未明确其发病机制,也无有效治疗措施。本文就近年来国内外学者对其相关危险因素研究进展做一综述,旨在进一步了解ARMD从而预防或减缓其发病,避免失明。

Age-related macular degeneration（AMD）, the most common cause of irreversible blindness over 50 years in developed countries, is a degenerative disease occurs with age. The prevalence rate in our country is also increasing by year and the pathogenesis is still undiscovered. In this review, we focus on the associated risk factors reported in recent years, aim to further understand the pathogenesis of AMD.