视网膜中央静脉阻塞性黄斑水肿的OCT与ERG的对比分析

Correlation between the optical coherence tomography and electroretinogram in retinal vein occlusion macular edema

目的:观察视网膜中央静脉阻塞性黄斑水肿的黄斑区视网膜厚度与视网膜电图(electroretinogram,ERG)各项参数(Cone-a,Cone-b和30Hz)变化的关系。方法:随机选择视网膜中央静脉阻塞患者25例25眼及25只对侧眼分别行明视闪光视网膜电图及光学相干断层扫描(optical coherence tomography,OCT)检查,明视闪光视网膜电图检查测各项参数的振幅和潜伏期,OCT测量黄斑区九部分的视网膜厚度,分析黄斑区形态参数与明视闪光视网膜电图各参数变化之间的关系。结果:黄斑区除颞侧外七个部位视网膜厚度与ERG的Cone-b和30Hz潜伏期相关。结论:研究发现视网膜中央静脉阻塞患者的黄斑区视网膜厚度与内层视网膜功能密切相关。

AIM： To evaluate the correlation between retinal thickness and photopic flash electroretinogram （ ERG ） parameters （ Cone a-wave, Cone b-wave, and 30Hz flicker ） in patients with central retinal vein occlusion （ CRVO） and macular edema. METHODS： A total of 25 patients （25 CRVO eyes and 25 unaffected fellow eyes ） with CRVO underwent the examination of optical coherence tomography （OCT） and photopic falsh ERG. The amplitude and implicit time of the ERG parameters were extracted from the ERG traces. Retinal thicknesses were measured by OCT in nine macular subfields. Then the correlations between ERG parameters and macular morphological parameters were analyzed. RESULTS： The Cone b-wave and 30Hz flicker implicit time were correlated with macular retinal thickness in seven out of nine subfields, excluding the temporal subfields. CONCLUSION： The retinal thickness of the macular edema may be associated with inner retinal function in CRVO patients.