垂体转移癌的临床诊治

Clinical diagnosis and treatment of pituitary metastases

目的:通过1例肺癌垂体转移病例报道,回顾分析本院另1例影像学诊断为垂体转移癌的病例,并复习相关文献,总结垂体转移癌的临床特点。方法:分析2例垂体转移癌的临床资料,整理复习近期国内外关于垂体转移癌的相关文献。结果:垂体转移癌患者临床表现多为尿崩、头痛、视物模糊等眼部症状,病情通常进展较快。影像学表现为鞍区骑跨鞍隔生长而呈"哑铃状"浸润性肿瘤。结论:患者出现垂体异常增大或伴有垂体病变的临床症状时,首先要考虑垂体转移,垂体转移癌病人预后极差。

Objective： To summary the clinical features of pituitary metastasis in order to improve the diagnostic accuracy of neoplasm metastasis of pituitary gland. Methods： To report a case of pituitary gland metastasis from lung cancer,retrospectively analyse another pituitary metastasis case by imaging diagnosis in our hospital and review the domestic and international literatures. Results： Diabetes insipidus,headache,blurred vision and other eye symptoms were often seen in neoplasm metastasis of pituitary gland. The disease is usually rapid progress. Imaging studies displayed that the lesions straddle sellae diaphragma in saddle area and showed infiltrative growth patterns,liking ＂ dumbbell- shaped＂. Conclusion： For cancer patients,if the pituitary abnormally increase or accompanied by clinical symptoms of pituitary disease,we must consider the pituitary metastasis,the prognosis is poor.