吸烟与饮茶交互作用对肺结核的影响

Impact of interaction between smoking and tea drinking on susceptibility to tuberculosis

目的:探讨男性人群中吸烟、饮茶及其交互作用对肺结核的影响。方法:对427例肺结核病人,410例健康对照采用病例对照研究方法分析吸烟、饮酒及其交互作用与肺结核的关系。采用自制的调查问卷收集资料。结果:吸烟是男性人群肺结核的危险因素,OR=1.62(1.15,2.30),P<0.05。饮茶是男性人群肺结核的保护因素,OR=0.58(0.42,0.78),P<0.05。吸烟与饮茶存在拮抗交互作用,交互作用超额相对危险度(RERI)为-0.24(-0.41,-0.07),P<0.05。结论:吸烟是肺结核的危险因素,饮茶是肺结核的保护因素,饮茶能部分拮抗吸烟的作用。在人群中特别是肺结核高危人群中推荐茶作为日常饮品,将可能减少结核病的发生,同时具有极高的可行性。

AIM：To explore the impact of smoking,tea drinking and their interaction on susceptibility to tuberculosis.METHODS：A total of 427 tuberculosis patients and 410 healthy controls were recruited to participate in this case-control study.Self-developed questionnaire was used to collect data.RESULTS：Smoking was a risk factor against TB,with OR=1.621（1.152,2.301）,P〈0.05.Tea drinking was a protective factor against TB,with OR=0.583（0.423,0.782）,P〈0.05.There were negative interactions between smoking and tea drinking,with a RERI of-0.24（-0.41,-0.07）,P〈0.05.CONCLUSION：Smoking could increase the risk of TB.Tea drinking could decrease the risk of TB.Tea drinking could soften the effect of smoking.Promoting the consumption of tea as daily drink among populations,particularly those with high TB risk,may reduce the incidence of TB in the population.