二维斑点追踪显像评价系统性红斑狼疮患者左心房功能

Evaluation of Left Atrial Function in Patients with Systemic Lupus Erythematosus by Two-dimensional Speckle Tracking Imaging

目的应用二维斑点追踪显像技术(two-dimensional speckle tracking imaging,STI)评价系统性红斑狼疮(SLE)患者左心房功能,探讨其临床应用价值.方法正常对照组40例健康志愿者,病例组40例SLE患者分别接受常规超声心动图检查,收集患者一般资料,采集心尖四腔心切面、心尖两腔心切面、心尖长轴切面动态二维图像,应用二维斑点追踪显像技术获取左心房侧壁基底段、房间隔基底段在左心室收缩期、舒张早期和舒张晚期的峰值应变率计算平均峰值应变率.结果与对照组比较,SLE组平均峰值应变率mSRs、mSRe降低及mSRa升高(P<0.05).结论二维斑点追踪显像技术能客观、准确观察到SLE患者左心房功能的变化,为临床早期诊断SLE患者左心房功能改变提供新指标.

Objective To evaluate left atrial （LA） function in patients with systemic lupus erythematosus （SLE） by two-dimensional speckle tracking imaging （STI） , and to explore the clinical value of STI. Methods Normal control group （40 healthy volunteers） and case group （40 SLE patients） underwent routine echocardiography examination, respectively. The general information of patients and apical four-chamber vengeful dynamic two-dimensional image were collected. Strain rates were analyzed using ST] during left ventricular systolic （SRs）, early diastole phase （SRe） and late diastolic （SRa） at the side wall of the basal segment of LA and septal basal segment. Results Strain rates decreased in SLE group by presenting SRs and SRe declined while SRa increased, compared with control group （P〈0.05） . Conclusion STI can observe changes of LA function in SLE patients objectively and accurately, which provides new indicators for early diagnosis of LA function in patients with SEE.