乳腺癌保乳术结合新辅助化疗法治疗乳腺癌的临床疗效观察

Clinical Effect of Breast Conserving Surgery Combined with Neoadjuvant Chemotherapy Treatment for Breast Cancer

目的探讨乳腺癌保乳术结合新辅助化疗法治疗乳腺癌的临床疗效.方法将2010年3月至2012年10月昆明医科大学第三附属医院所收治的乳腺癌患者90例分为2组,观察组采用保乳术结合新辅助疗法,对照组采用传统根治术疗法.术后保证化疗和随访的跟进,综合比较2组的临床疗效.结果观察2组在术中手术时间、术中出血量、术后恢复时间、并发症发生率、术后恢复水平等方面的数据指标,得出观察组明显优于对照组,差异有统计学意义(P<0.05).结论保乳术结合新辅助化疗治疗乳腺癌相较于改良根治术,优势明显,表现在术中各方面以及术后患者的身体的康复和自信心的重拾,值得在临床推广应用.

Objective To investigate the clinical efficacy of breast conserving surgery combined with neoadjuvant chemotherapy treatment for breast cancer. Methods 90 breast cancer patients from March 2010 to October 2012 of our hospital were divided into the observation group and the control group. The observation group was treated with breast-conserving surgery combined with neoadjuvant therapy, while the control group was treated with traditional radical mastectomy. The chemotherapy postoperative and follow-up were made, and the clinical efficacies of the two groups were compared comprehensively. Results Various indicators such as surgery operative time, blood loss, postoperative recovery time, incidence of complications, and postoperative recovery levels in the observation group were better than the control group, with a statistical difference （P 〈 0.05） Conclusion Compared with modified radical mastectomy, breast conserving surgery combined with neoadjuvant chemotherapy for breast cancer has obvious advantages in all aspects during operation, rehabilitation and restoring patients＇ confidence. It is worth to popularize in the clinical application.