皮肤原位再生技术治疗老年压疮临床疗效研究

Clinical Study of Treatment Effect of In Situ Skin Regeneration Technology on Elderly Pressure Ulcer

目的对比观察皮肤原位再生技术治疗老年压疮的临床疗效。方法将57例老年压疮患者按照随机数字表法随机分为治疗组(26例)和对照组(31例),在积极治疗原发病的同时,治疗组采用湿润烧伤膏联合外科清创术治疗;对照组采用磺胺嘧啶银软膏联合外科清创术治疗,90 d后根据统一评估标准评估两组疗效。结果治疗组90 d治愈率为76.92%(20/26),对照组90 d治愈率为45.16%(14/31),两组患者90 d治愈率经统计学处理,差异具有统计学意义(x^2=4.75,P<0.01)。结论皮肤原位再生技术治疗老年压疮疗效显著,操作简便,损伤较小,止痛及防治感染效果较好,值得临床推广应用。

Objective To comparatively observe the clinical efficacy of in situ skin regeneration technology in the treatment of elderly pressure ulcer .Methods All of the 57 elderly patients with pressure ulcer were randomly divided into treatment group （26 cases） and control group （31 cases） according to random number table .While proactively treating the primary diseases, the treatment of MEBO combined with surgical debridement technique was also applied to the treatment group;and silver sulfadiazine ointment combined with surgical debridement technique was applied to the control group . Treatment efficacy of both groups was determined according to unified assessment standards 90 days later .Results The 90 d cure rate was 76.92%（ 20/26 ） for treatment group and 45.16% （ 14/31 ） for control group .There was significant difference statistically between the cure rate of the two groups （χ^2 =4.75 and P〈0.01 ） .Conclusion Applying in situ skin regeneration technology to treat elderly pressure ulcer has the characteristics of remarkable efficacy , simple operation , less injury and good effect on preventing and treating infections , worthy of clinical promotion and application .