摘要
目的 比较FP-7型与S2型Ahmed青光眼引流阀治疗难治性青光眼的疗效及并发症有无差异.方法 回顾性病例研究.分析于沧州市中心医院眼科分别行S2型(26例26眼)和FP-7型(23例23眼)Ahmed青光眼引流阀植入术的难治性青光眼患者的临床资料,对2组的眼压变化、手术成功率、术后并发症等进行比较.术前、术后眼压比较及2个观察组降眼压效果比较采用重复测量资料的方差分析;手术成功率的计算采用寿命表法,比较采用log-rank检验;并发症发生率的比较采用Fisher确切概率法.结果 S2组术前眼压为(38.19±10.56)mmHg,术后1、6、12、24个月的眼压分别为(14.54±4.11)mmHg、(15.83±5.76)mmHg、(17.19±4.96)mmHg、(18.84±5.28)mmHg; FP-7组术前眼压为(39.91 ±9.12)mmHg,术后各时间点眼压分别为(14.41±5.14)mmHg、(15.95±4.32)mmHg、(17.11±4.75)mmHg、(19.06±6.55)mmHg.2组降眼压效果差异无统计学意义.至最后一次随访S2组的累积总成功率和累积完全成功率分别为82%和74%,FP-7组分别为80%和75%,2组比较差异无统计学意义.结论 FP-7型与S2型Ahmed青光眼引流阀治疗难治性青光眼的降眼压效果相当,FP-7型的术后并发症发生率不高于S2型.
Objective To compare the efficacy of using of FP-7 and S2 Ahmed glaucoma valve implantations (AGI) for refractory glaucoma and to monitor postoperative complications.Methods A retrospective study was conducted to document patients with refractory glaucoma who underwent S2 (26 eyes from 26 patients) or FP-7 (23 eyes from 23 patients) AGI in the Center Hospital of Cangzhou.The change in IOP,the surgical success rate,and postoperative complications were recorded and analyzed.A variance analysis of repeated measurement data was used for comparison of preoperative and postoperative IOP and the effect of reducing IOP in the 2 observation groups.Cumulative survival rates were calculated using survival analysis and compared using a log-rank.The Fisher exact test was used for the comparison of complication rates.Results IOP was reduced from 38.19±10.56 mmHg to 14.54±4.11,15.83±5.76,17.19±4.96,and 18.84±5.28 mmHg at month 1,month 6,month 12,and month 24 postoperatively in the S2 group and reduced from 39.91±9.12 mmHg to 14.41±5.14,15.95±4.32,17.11±4.75,and 19.06±6.55 mmHg in the FP-7 group.There was no statistically significant difference between the 2 groups for their effect on lowering IOP.At the last follow-up,the cumulative probabilities of success and of total success were 82% and 74% in the S2 group,and 80% and 75% in the FP-7 group.There was no statistically significant difference between the 2 groups.Conclusion FP-7 AGI was equal to S2 AGI in reducing IOP in refractory glaucoma.The complication rate in the S2 group was no higher than it was in the FP-7 group.
出处
《中华眼视光学与视觉科学杂志》
CAS
2014年第10期599-603,共5页
Chinese Journal Of Optometry Ophthalmology And Visual Science
关键词
青光眼引流植入物
青光眼
眼内压
治疗结果
Glaucoma drainage implant
Glaucoma
Intraocular pressure
Treatment outcome