虫草治肝片治疗慢性乙型肝炎毒热未清气阴两虚证316例

Chongcao Zhigan Pill Treating 316 Cases of Chronic Hepatitis B Viral Hepatitis of Both Qi and Yin Deficiency with Heat Toxin Syndrome

目的评价虫草治肝片治疗慢性乙型病毒性肝炎(毒热未清,气阴两虚证)的临床疗效及安全性。方法采取随机、双盲、阳性药平行对照的方法,将受试者分为治疗组和对照组其中试治疗316例,对照组106例。两组分别服用虫草治肝片(5片/次,3次/d)和苦参素胶囊安慰剂(2粒/次,3次/d),连服90天;结果治疗组愈显率、总有效率分别为41.77%、84.18%;对照组分别为34.91%、67.92%,两组间比较有统计学意义(P<0.05),治疗组均明显优于对照组。结论虫草治肝片治疗慢性乙型病毒性肝炎(毒热未清,气阴两虚证)疗效显著,且未发现不良反应。

Objective to evaluate the clinical efficacy and safety of Chongcao Zhigan Pill in treating chronic hepatitis B viral hepatitis （both qi and yin deficiency with heat toxin syndrome）. Methods took a randomized, double-blind, pos- itive drug parallel contrast method, 316 cases were divided into treatment group and control group , control group had 106 cases. The two groups were respectively taken Cbongcao Zhigan pill （5 / time, 3 times/d） and Kusen capsule placebo （/2 times, 3 times/d）, for 90 days; Results the treatment group got markedly effective rate and total effective rate was 41.77 % , 84.18 % ; The control group were 34.91% , 67.92 %, comparison between the two groups was statistically significant （ P〈 O. 05 ）, the treatment group was significantly better than the control group. Conclusion Chongcao Zhigan pill treat chronic hepatitis b viral hepatitis （beth qi and yin deficiency with heat toxin syndrome） , curative effect is out- standing, and no adverse reactions.