中医慢性肝病患者报告结局指标量表建立的理论结构模型构想

An Establishment of Theoretical Structure of PRO Questionnaire in Treating Chronic Liver Disease by Chinese Medicine

为了建立具有中医特色的慢性肝病患者报告结局指标(patient reported outcomes,PRO)量表,本研究遵循国际PRO量表研制规范,结合"形神统一"、"天人合一"、"肝体阴而用阳"、"七情"等中医学理论学说,构建中医慢性肝病PRO量表理论结构模型。包括生理、心理、独立性以及社会自然4大领域。其中生理领域包含血虚、阴虚、出血、气机失畅、脾胃运化失常、胆汁排泄异常6大方面;心理领域包含肝脏相关情绪与一般疾病情绪两方面;独立性领域包含日常生活与学习工作两方面;社会自然领域包含社会关系、社会环境以及自然适应能力3方面。

By reviewing research contents of patient-reported outcome（ PRO） and discussing Chinese medicine（ CM） theories related to chronic liver disease（ CLD）,we have followed international PRO questionnaire development specification,combined CM theories such as uniformed spirit and body,correspondence between human and the universe,yin in property and yang in function of Gan,and seven emotions,and constructed theoretical structure of PRO questionnaire of treating CLD,including four major areas as physiology,psychology,independence,and society and nature. Of them,the physiological field contained six aspects such as blood deficiency,yin deficiency,bleeding,disorder of qi movement,improper transformation and transportation of Pi-Wei,and abnormal biliary excretion. The psychological field contained two aspects：Gan-related emotions and general disease related emotions. The independence field contained two aspects： daily life and study and work. The field of society and nature contains three aspects： social relations,social environment,and natural adaptability.