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氯喹性视网膜病变一例 被引量：2

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摘要 患者女性,37岁.因视力模糊伴眼前不规则黑影遮挡,于2013年8月7日就诊于解放军总医院眼科.既往患系统性红斑狼疮21年,自1992年开始口服氯喹（Chloroquine）,0.1 ～0.2g/次,5次/d,每周5 d,分别于1992、1995、1997、2002年在外院检查,视力为1.0～1.5,眼底均正常.2005年检查视力为1.2,发现双眼黄斑呈典型靶心样改变,诊断为氯喹性视网膜病变.此后改服硫酸羟氯喹,0.1 g/d,每周服5d.2006年来我院检查,双眼矫正视力为1.0,发现双眼黄斑对称分布圆盘状红褐色病变,边界清,诊断为氯喹性黄斑病变.停止服用硫酸羟氯喹半年后,因全身症状反复,遂重新服药（0.1 g/d）至今.服用氯喹总量超过2.0 kg.
作者 何守志 张鲲 王玮
机构地区 解放军总医院眼科
出处 《中华眼科杂志》 CAS CSCD 北大核心 2014年第11期843-844,共2页 Chinese Journal of Ophthalmology
关键词 硫酸羟氯喹 视网膜病变 系统性红斑狼疮 视力模糊 解放军总医院 矫正视力 对称分布 黄斑病变
分类号 R774.1 [医药卫生—眼科]
  • 相关文献

参考文献4

  • 1马晓昀,何琳萍.氯喹毒性视网膜病变二例[J].中华眼科杂志,2010,46(5):463-465. 被引量：6
  • 2李春,刘恩生,穆荣,栗占国.羟氯喹所致视网膜病变的文献分析[J].药物不良反应杂志,2010,12(1):21-25. 被引量：19
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二级参考文献35

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共引文献22

同被引文献35

  • 1Bhavsar KV, Mukkamala LK, Freund KB. Multimodal imaging in a severe case of hydroxyehloroquine toxicity[J]. Ophthalmic Surg Lasers Imaging Retina, 2015, 46(3): 377-379. DOI: 10. 3928/23258160-20150323-14.
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中华眼科杂志
2014年 第11期

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