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PCT、hs-CRP、SAA对细菌与病毒感染的鉴别作用 被引量:41

The roles of PCT,hs-CRP and SAA in the discrimination of bacterial and viral infections
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摘要 目的探讨降钙素原(PCT)、超敏C-反应蛋白(hs-CRP)及血清淀粉样蛋白A(SAA)对病毒感染与细菌感染的鉴别作用。方法分别测定病毒感染组、细菌感染组、真菌感染组、混合感染组及非感染组患者的PCT、hs-CRP和SAA浓度,分析PCT、hs-CRP和SAA对病毒感染和细菌感染的诊断效能。结果细菌感染组、病毒感染组、真菌感染组、混合感染组及非感染组间比较,PCT、hs-CRP和SAA差异均有统计学意义(P<0.05)。PCT用于细菌与病毒感染的鉴别诊断效能最大。结论血清PCT、hs-CRP和SAA检测可用于细菌感染性疾病的诊断及其与病毒感染性疾病的鉴别。 Objective To explore the effects of PCT,hs-CRP and SAA on the discrimination of bacterial and viral infections.Methods The concentrations of PCT,hs-CRP and SAA in viral infection group,bacterial infection group,fungal infection group,mixed infection group and non-infection group were detected respectively.The diagnostic efficiency of PCT,hs-CRP and SAA for the differential diagnosis of bacterial and viral infections were analyzed.Results Among viral infection group,bacterial infection group,fungal infection group,mixed infection group and non-infection group,there were significant differences in the concentrations of PCT,hs-CRP and SAA(P〈0.05).PCT worked at the maximum efficiency for the differential diagnosis of bacterial and viral infections.Conclusion The detection of serum PCT,hs-CRP and SAA can be used for the diagnosis of bacterial infections and the differential diagnosis with other infections.
出处 《国际检验医学杂志》 CAS 2014年第22期3048-3050,共3页 International Journal of Laboratory Medicine
关键词 降钙素原 C反应蛋白 血清淀粉样蛋白 procalcitionin C reactive protein serum amyloid protein
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参考文献13

  • 1Garner JS,Jarvis WR, Emori TG, et al. CDC definitions for noso- eomial infections,1988[J]. Am J Infect Control,1988 ,16(3) :128- 140.
  • 2中华人民共和国卫生部.医院感染诊断标准(2001年试行)[S/OL].[2011-06-18].http://www.moh.gov.cn/publicfiles/business/htmlfiles/mohyzs/s3593/200908/42455.htm.
  • 3侵袭性肺部真菌感染的诊断标准与治疗原则(草案)[J].中华内科杂志,2006,45(8):697-700. 被引量:866
  • 4Ramirez P, Garcia MA, Ferrer M, et al. Sequential measurements of procalcitonin levels in diagnosing ventilator-associated pneumo- nia[J]. Eur Respir, 2008,31 (2): 356-362.
  • 5Azoulay E,Mokart D,Lambet J, et al. Diagnostic strategy for he- matology and oncology patients with acute respiratory failure:ran- domized controlled trial [J], Am J Respir Crit Care Med, 2010, 182(8) : 1038-1046.
  • 6Charles PE,Castro C,Ruiz-Santana S, et al. Serum procalcitonin levels ia critically ill patients colonized with Candida: new clues for the early recognition of invasive candidiasis? [J]. Intensive Care Med,2009,35(12) :2146-2150.
  • 7张守印,贺金荣,张双宅,刘劼,蔡虹,马凤琴,张建华,海荣,俞东征,徐建国.PCT早期鉴别诊断细菌和病毒感染及其在疾病控制中的应用[J].中国卫生检验杂志,2007,17(12):2235-2237. 被引量:27
  • 8Mtiller B, Becker KL, Schichinger H, et al. Calcitonion precursors are reliable markers of sepsis in a medical intensive care unit[J], Crit Care Med, 2000,28 (4) : 977-983.
  • 9Shaoul R, Lahad A, Tamir A, et al. Srugo I C reactive protein (CRP) as a predictor for true bacteremia in children[J]. Med Sci Monit,2008,14(5) :255-261.
  • 10Katayama T, Nakashima I-I, Takagi C, et al. Serum amyloid A protein as a predictor of cardiac rupture in acute myocardial in- farction patients following primary coronary angioplasty[J]. Citc.

二级参考文献13

  • 1黄晓军.血液病/恶性肿瘤患者侵袭性真菌感染的诊断标准与治疗原则(草案)[J].中华内科杂志,2005,44(7):554-556. 被引量:423
  • 2Stevens DA,Kan VL,Judson MA,et al.Practice guidelines for diseases caused by Aspergillus.Infectious Diseases Society of America.Clin Infect Dis,2000,30:696-709.
  • 3Ascioglu S,Rex JH,de Pauw B,et al.Defining opportunistic invasive fungal infections in immunocompromised patients with cancer and hematopoietic stem cell transplants:an international consensus.Clin Infect Dis,2002,34:7-14.
  • 4Denning DW,Kibbler CC,Barnes RA,et al.British Society for Medical Mycology proposed standards of care for patients with invasive fungal infections.Lancet Infect Dis,2003,3:230-240.
  • 5Pappas PG,Rex JH,Sobel JD,et al.Guidelines for treatment of candidiasis.Clin Infect Dis,2004,38:161-189.
  • 6Slavin MA,Szer J,Grigg AP,et al.Guidelines for the use of antifungal agents in the treatment of invasive Candida and mould infections.Intern Med J,2004,34:192-200.
  • 7Saag MS,Graybill RJ,Larsen RA,et al.Practice guidelines for the management of cryptococcal disease.Infectious Diseases Society of America.Clin Infect Dis,2000,30:710-718.
  • 8Guerin S. Evaluation of the detection of procalcitonin by an immuno -chromatography test : brahms PCT - Q [ J ]. Ann Biol Clin, 2000,58 (5) :613 -614.
  • 9Maruna P, Nedelnikova K, Gurlich R. Physiology and genetics of procalcitonin [ J ]. Physiol Res,2000,49 ( Suppl 1 ) :S57 - 61.
  • 10Oberhoffer M, Stonans I, Russwrm S, et al. Procalcitonin expression in human peripheral blood mononuclear cells and its modulation by lipopolysacchrides and sepsis -related cytokines in vitro [ J ]. J Lab Clin Med, 1999,134( 1 ) :49 -55.

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