286株金黄色葡萄球菌临床分布及耐药性分析

Analysis on clinical distribution and drug resistance of 286 strains of Staphylococcus aureus

目的分析2013年住院及门诊患者送检微生物培养标本分离得到的金黄色葡萄球菌临床分布及耐药性情况。方法对2013年分离得到的金黄色葡萄球菌进行细菌培养鉴定及药敏试验,并对结果进行分析。结果共分离得到286株金黄色葡萄球菌,耐甲氧西林金黄色葡萄球菌(MRSA)检出率为46.85%。呼吸道标本中的金黄色葡萄球菌和MRSA检出率均为最高。金黄色葡萄球菌主要分布于ICU、神经外科、创伤骨科、呼吸内科等临床科室。金黄色葡萄球菌对青霉素和氨苄西林耐药率较高,多数抗菌药物对甲氧西林敏感的金黄色葡萄球菌(MSSA)与MRSA的耐药率存在差异。结论监测金黄色葡萄球菌耐药性,对临床合理选择抗菌药物十分重要。

Objective To analyze the clinical distribution and drug resistance of Staphylococcus aureus isolated from the specimens of inpatient and outpatient in 2013.Methods All of the isolated Staphylococcus aureus were identified and tested drug sensitivity in 2013,and the results were analyzed.Results 286 strains of Staphylococcus aureus were isolated with the detection rate of MRSA accounting for 46.9%.The respiratory specimens had the highest detection rates of Staphylococcus aureus and MRSA.The isolated strains of Staphylococcus aureus were mainly distributed in ICU,Department of Neurosurgery,Department of Orthopedic trauma,and Department of Respiratory Medicine.The isolated Staphylococcus aureus had high drug resistant rates to penicillin and ampicillin.The drug resistant rates of most of the drugs were different between MSSA and MRSA.Conclusion Monitoring the drug resistance of Staphylococcus aureus is very important to rational choice of antimicrobial agents.