摘要
目的回顾性研究临床分离铜绿假单胞菌的标本来源、病区分布、耐药状况及其变迁。方法采用Microscan Walkaway40鉴定药敏系统及传统手工方法对2002-2012年医院各类临床送检标本中分离到的1 114株铜绿假单胞菌进行鉴定及药敏试验,对结果进行统计分析。结果 1 114株分离的铜绿假单胞菌中,有64.18%来自呼吸道标本。铜绿假单胞菌感染主要发生在重症监护病房（ICU）病房,占49.64%。2002-2012年间,铜绿假单胞菌对19种抗菌药物的耐药率总体呈上升趋势。结论铜绿假单胞菌常引起呼吸道感染,其耐药机制复杂,可选择的抗菌药物有限。
Objective To retrospective analyze the specimens and wards distribution and the drug resistance changes of clinical isolated Pseudomonas aeruginosa.Methods 1 114 strains of Pseudomonas aeruginosa were isolated from a variety of clinical specimens for the identification and susceptibility testing by using Microscan Walkaway40 identification and antibiotic susceptibility analysis system and manual method from 2002 to 2012.And the results were analyzed.Results In all of the 1 114 isolated Pseudomonas aeruginosastrains,there were 64.18% of them from respiratory specimens.Pseudomonas aeruginosa infection occured mainly in the ICU wards（49.64%）.From 2002 to 2012,the drug resistance rates of Pseudomonas aeruginosa to 19 kinds of antibacterial drugs increased year by year.Conclusion Pseudomonas aeruginosa often causes respiratory tract infection,and its mechanism of drug resistance is complex.There are few alternative antimicrobial drugs for the treatment of Pseudomonas aeruginosainfection.
出处
《国际检验医学杂志》
CAS
2014年第22期3072-3073,共2页
International Journal of Laboratory Medicine
关键词
铜绿假单胞菌
抗菌药物
耐药
Pseudomonas aeruginosa
antimicrobial agents
drug resistance
