抗菌药物在剖宫产围手术期中的应用分析

Applied analysis on perioperative antibiotics using in cesarean section

目的:调查分析剖宫产围手术期患者抗菌药物使用情况,并对用药的合理性进行评价。方法:回顾性分析180例剖宫产围手术期患者的临床资料,对所用抗菌药物采用频度分析法进行分析。结果:所有患者抗菌药物使用率最高的为奥硝唑,消耗量最高的为奥硝唑,销售金额最高的为奥硝唑、头孢替安,用药频度最高的为奥硝唑,使用比较合理的药物为青霉素钾、头孢替安及奥硝唑;使用最不合理的药物中青霉素、头孢唑林的金额排序/DDDs(用药人次数)排序均高于1;头孢美唑的金额排序/DDDs(用药人次数)排序值最低,且低于1。单独用药比例仅为0.56%,联合用药中二联用药所占比例最高,为76.67%。结论:剖宫产患者围手术期所用抗菌药物存在使用时间较长、用法用量不当的问题,应该加强监管力度,提高医院药物的合理使用水平。

To investigate the cesarean perioperative usage in patients, and the rationality of drug evaluation.Methods： A retrospective analysis in February 2012 to August 2013 in our hospital for treatment of cesarean perioperative clinical information on the use of antimicrobial agents for statistics, and use frequency analysis method for analysis.Results： All patients with the highest rates of antibiotic Ornidazole, the highest consumption of Ornidazole, the highest amount of sales Ornidazole, cefotiam, the highest frequency of drug use Ornidazole use reasonable potassium penicillin drugs, cefotiam, ornidazole; most unreasonable use drugs penicillin, cefazolin amount of sorting/DDDs （medication on the number） were higher than a sort; cefmetazole the amount of sorting/ DDDs （medication on the number） Sort lowest value, and less than 1.Ratio of only 0.56% monotherapy, combination therapy of two drugs highest proportion is 76.67%. Conclusion： Perioperative cesarean section used antibiotics exists that use a longer time, the problem of improper dosage should strengthen supervision and improve the rational use of medicines in hospitalslevel.