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河北省唐山地区乙型肝炎病毒血清标志物定量检测与分布特征分析 被引量:5

The Detection in Quantitative serum markers of hepatitis B virus and distribution characteristics in Tangshan area of Hebeiprovince
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摘要 目的通过分析河北省唐山地区乙型肝炎病毒血清学标志物(HBVM)定量模式及性别分布特征。从而指导本地区乙型肝炎的预防、诊断;乙肝抗病毒的治疗与乙肝的防控。方法应用电激化学发光技术在LICA HT免疫分析仪上检测乙型肝炎病毒血清学标志物五项定量。采用SPSS17.0对乙型肝炎病毒血清学定量检测结果进行统计学分析。结果综合统计711人,在各种乙型肝炎病毒血清学类型中,共检出乙型肝炎血清学两对半定量模式16种。其中,乙型肝炎病毒HBVM五项最主要模式是"1,5"阳性占15.471%(110/711)、"1,3,5"阳性占20.394%(145/711)、"1,4,5"阳性占31.928%(227/711)阳性;其次是阴性占2.672%(19/711)、"2"阳性占7.595%(54/711)、"5"阳性占4.219%(30/711)、"2,5"阳性占3.235%(23/711)、"4,5"阳性占6.470%(46/711)、"2,4,5"阳性6.048%(43/711);其它7种低频模式检出率为0.281%-0.422%。结论本地区人群中HBVM"1,4,5"阳性检出率最高,其次是"1,3,5"阳性的检出率。单"2"阳性的抗体浓度多位于100-900mIU/mL之间,各年龄段均有单"2"阳性的抗体浓度>1000mIU/mL。单"5"阳性的23例/30例的抗体浓度>60PEIU/mL。 Objective By analyzing the Tangshan region in Hebei province serological markers of hepatitis B virus(HBVM)quantitative model and its gender-related distribution.Easy to guide the region of hepatitis B prevention,diagnosis,antiviral treatment of hepatitis B and hepatitis B control.Methods By applying electric shock chemiluminescence immunoassay analyzer at LICA HT on the detection of HBV serological markers five quantification.Using SPSS17.0for quantitative detection of hepatitis B virus serology results were statistically analyzed.Results General Statistics 711 people in a variety of types of hepatitis B virus serology of hepatitis B serological detection of two pairs of semi-quantitative mode 16 kinds.Among them,hepatitis B virus HBVM five main mode is"1,5"accounted for 15.471% positive(110/711),"1,3,5"accounted for 20.394% positive(145/711),"1,4,5"representing 31.928% positive(227/711)positive;followed negative account 2.672%(19/711)"2"accounted for 7.595% positive(54/711),"5"accounted for4.219% positive(30/711),"2,5"positive account 3.235%(23/711),"4,5"positive account 6.470%(46/711),"2,4,5"positive 6.048%(43/711);seven other low mode detection rate of 0.281%-0.422%.Conclusion The regional population HBVM "1,4,5"positive detection rate is highest,followed by"1,3,5"positive detection rate.Single"2"positive antibody concentrations were located between 100-900mIU/mL of all ages have a single"2"positive antibody concentrations〉1 000mIU/mL.Single"5"positive 23cases/30 cases of antibody concentrations〉60PEIU/mL.
出处 《中国实验诊断学》 2014年第11期1837-1840,共4页 Chinese Journal of Laboratory Diagnosis
基金 河北省科技厅课题资助(20131041)
关键词 乙型肝炎病毒(HBV) 化学发光法 乙型肝炎病毒标志物(HBVM) 定量 Hepatitis B virus(HBV) Light initiated chemiluminescence Hepatitis B virus markers(HBVM) Quantitative
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