双针穿刺溶栓治疗人造血管栓塞的效果分析

Double-Needle Thrombolytic Therapy Effectiveness Analysisof Artificial Blood Clots

目的总结动静脉内瘘血栓形成溶栓治疗的方法和经验以及对其治疗效果进行分析。方法治疗前后均采用彩色超声检查观察内瘘的情况。选择动、静脉吻合口两处作为穿刺点,通过双针微量泵入尿激酶持续灌注局部溶栓治疗,以恢复人造血管再通。比较治疗前后患者的纤维蛋白原(Fbg)、凝血酶原时间(PT)、肝肾功能、凝血酶时间(TT)、部分凝血酶活化时间(aPTT),并观察不良反应。结果 38例患者进行溶栓,30例溶栓成功(79%),未见不良反应。30例瘘管全部在溶栓后再通。溶栓前后患者的Fbg、PT、肝肾功能、TT、aPTT经过比较无显著差异。治疗的成功率与患者血栓形成时间长短及静脉端流出道状态有关结论双针穿刺法微量泵入尿激酶及时溶栓治疗安全、有效,成功率高,并无不良反应,具有很高的临床价值,可作为人造血管溶栓处理的理想选择。

Objective Summary of arteriovenous fistula thrombosis thrombolytic therapy methods and experience as well as to analyze its therapeutic effect Methods Before and after treatment are used in the case of the color Doppler ultrasound observation fistula.Select the arterial and venous anastomosis two asthe puncture point,pumped through a micro-needle local thrombolysis with urokinase infusion to restore artificial recanalization.Before and after treatment in patients with fibrinogen（Fbg）,prothrombin time （PT）,liver and kidney function,thrombin time （TT）,activated partial thromboplastin time （aPTT）,and observed adverse reactions.Results 38 cases of patients with thrombolytic therapy,30 cases of successful thrombolysis （79%）,no adverse reactions.30 cases of fistula after all pass in thrombolysis.After thrombolysis in patients with Fbg,PT,liver and kidney function,TT,aPTT after no significant differences.Success rate of thrombosis in patients with duration of treatment and the state of venous outflow tract.Conclusion Double-needle method micro pump timely thrombolytic therapy with urokinase into safe,effective,high success rate,there is no adverse reaction,with a high clinical value can be used as an ideal choice for artificial blood vcsscls thrombolytic treatment.