摘要
CO-029作为四跨膜蛋白超家族的重要成员之一,已有研究显示其在促进肿瘤侵袭与转移中的重要作用,但其具体机制仍知之甚少。研究明确其作用机制,有揭示肿瘤发生发展过程机制,作为预测肿瘤的进展及预后,进而开发新的肿瘤靶向治疗药物的潜在临床价值。
CO-029 belongs to the tetraspanins family, and has been revealed to play an important role in invasion and metastasis of carcinoma. However, how CO-029 promotes cancer invasion and metastasis is still poorly understood. Its explicit mechanisms in the development of tumor probably indicates that CO-029 has great potential clinical value in predicting the progression and the prognosis of cancer, and may be a potent molecular therapeutic target for cancer.
出处
《海南医学》
CAS
2014年第21期3191-3194,共4页
Hainan Medical Journal
