产前超声诊断胎儿神经母细胞瘤的临床研究

Clinical Study of ultrasound diagnosis on neuroblastoma in fetus

目的探讨胎儿神经母细胞瘤(neuroblastoma,NB)的超声表现及其超声诊断的价值。方法根据成都市妇女儿童中心医院超声科2009年2月至2013年10月产前超声检出的8例胎儿NB及其出生后手术及病理证实,回顾性分析胎儿各个时期的产前超声图像。结果 8例胎儿中,肿瘤位于胸腔/纵隔4例,来源于肾上腺者4例;8例产前均做出正确诊断,胎儿出生后,均由CT、MRI及产后超声证实,手术病例7例,术前超声诊断符合率100%。结论超声可以诊断胎儿NB,为临床早期干预提供依据。

Objective To explore the ultrasound feature of neuroblastoma（ NB） in fetus and the diagnosis value of ultrasound.Methods According to prenatal ultrasonography and postoperative pathological diagnosis,8 cases of NB in fetus in Women and Children＇s Central Hospital of Chengdu City from February 2009 to October 2013 were selected,a retrospective analysis of ultrasound images of fetus in different periods were made. Results 4 cases that the tumor were located in chest / mediastinum,4 cases in adrenal gland. All cases were diagnosed correctly through prenatal ultrasound and the diagnosis were proved to be correctly through CT and MRI after birth. 7 cases resorted to surgery afterwards,the postoperative ultrasound diagnosis was 100% correctly. Conclusion NB in fetus can be diagnosed by ultrasound,which can provide basis for early clinical intervention.