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阻塞性睡眠呼吸暂停综合征与心血管疾病

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摘要 阻塞性睡眠呼吸暂停综合征(OSAS)是一种病因十分复杂而又尚未完全阐明的病理状态,属睡眠中呼吸调节紊乱。这种病理状态不仅有睡眠打鼾和日间极度嗜睡(EDS ),还由于低通气或呼吸暂停引起反复发作的低氧高碳酸血症,可导致心肺和其他重要生命器官并发症,甚至发生猝死。因此OS-AS是一种有潜在致死性的睡眠呼吸紊乱性疾病。目前国际上多数学者认为OSAS的定义是:睡眠时口鼻气流停止≥10 s ,每小时呼吸暂停加低通气5次以上,即睡眠呼吸紊乱指数(RDI )>5,或每晚7 h呼吸暂停加呼吸低通气达30次以上者。我国内地流行病学调查资料表明,伴有嗜睡症状,OSAS在成年人中的患病率为3%~5%[1]。
作者 何海潇
出处 《山西医药杂志》 CAS 2014年第21期2520-2522,共3页 Shanxi Medical Journal
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参考文献19

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